李社增，研究员，硕士研究生导师，享受政府特殊津贴专家，河北省有突出贡献中青年专家，河北省“三三三人才工程”第二层次人选。1985~1989年在北京农业大学植保系植物病理学专业学习，获农学学士专业；1999~2002年在中国农业科学院研究生院微生物专业学习，并获理学硕士学位。主要从事植物病理学、棉花抗病性鉴定、微生物杀菌剂、微生物抑菌蛋白和抑病基因研究。1998~1999年，在Lethbridge Research Centre, Agriculture and Agri-Food Canada作访问学者；2008年12月-2009年6月在USDA-ARS-MSA, Biological Control of Pests Research Unit, National Biological Control Laboratory作高访学者。兼任生物农药和生物防治产业技术创新战略联盟副理事长。

主持和承担的重要课题

• 国家重点发计划专题“土传病虫害防治、微生物区系与根域生境优化关键技术”，2022-2027

• 国家重点发计划课题“高效细菌杀菌剂的研制与示范”，2017-2020

• 国家863计划“微生物杀菌剂研究与产品创制”—子课题“细菌类杀菌剂研究与产品创制”，2011-2015

• 国家转基因生物新品种培育重大专项“转基因抗虫杂交棉新品种育繁推及产业化”—子项目“转基因抗虫杂交棉病虫害综合治理技术”，2012-2015

• 科技部成果转化项目“微生物杀菌剂10亿芽孢/克枯草芽孢杆菌可湿性粉剂中试及示范”，2009-2011。

• 河北省财政专项“河北省农作物病虫害防治技术研究与应用”，2011。

代表性成果

• 2019年度“防治果蔬白粉病和灰霉病的微生物杀菌剂创制及产业化”获河北省科技进步一等奖

• 2014年度“生物农药高效微生物杀菌剂的创制及应用”获河北省技术发明一等奖。

• 2010年度“芽孢杆菌生物杀菌剂的研制与应用”获国家进步二等奖

• 2010年度“枯草芽孢杆菌NCD-2防治作物黄萎病生物农药的研制及产业化”获河北省科技进步一等奖。

• 2009年度“芽孢杆菌生物杀菌剂的研制与应用”获教育部科技进步二等奖

• 2007年度“棉花黄萎菌微菌核际拮抗微生物对微菌核消长的影响”获河北省科技进步三等奖。

发明专利

• 防治棉花黄萎病的菌株及其菌剂的制备方法，发明专利ZL200310109619.8

• 一种枯草芽孢杆菌及其菌剂和应用，发明专利ZL200610152019.3

• 一种枯草芽孢杆菌及其菌剂和应用，发明专利ZL200710121275.0

• 一种坚强芽孢杆菌及其菌剂和应用，发明专利ZL200710121274.6

• 一种高效定向筛选作物土传病害生防菌的方法，发明专利ZL201010144469.4

• 用于鉴定芽孢杆菌的通用引物以及使用它们的分类方法，发明专利ZL201110142323.0

• 一种用于防治棉铃疫病的短小芽孢杆菌及其微生物菌剂，发明专利ZL201210028108.2

• 一种用于防治棉铃疫病的萎缩芽孢杆菌及其微生物菌剂，发明专利ZL201210028087.4

• 一种防治黄瓜霜霉病的枯草芽孢杆菌及其微生物菌剂，发明专利ZL201210028079.X

• 一种用于防治黄瓜霜霉病的摩加夫芽孢杆菌及其微生物菌剂，发明专利ZL201210028098.2

• 一种防治黄瓜霜霉病的枯草芽孢杆菌及其微生物菌剂，发明专利ZL201210028103.X

• 一种利用物理隔离材料防治棉铃疫病的方法，发明专利ZL201310051117.8

• 氯化镁在提高枯草芽孢杆菌芽孢耐热性上的应用，发明专利ZL201310079071.0

• 一种用于防治棉花黄萎病的解淀粉芽孢杆菌及其应用，发明专利ZL201510742977.5

• 一种防治番茄灰霉病的解淀粉芽孢杆菌及其应用，发明专利ZL201510736659.8

• 一种防治番茄灰霉病的解淀粉芽孢杆菌及其微生物菌剂，发明专利ZL201510742976.0

• 枯草芽孢杆菌HMB19198在防治黄瓜白粉病上的应用，发明专利ZL201610879296.8

• 一种防治作物黄萎病的解淀粉芽孢杆菌及其微生物菌剂，发明专利ZL201510736549.1

• 一种用于防治作物立枯病的解淀粉芽孢杆菌及其应用，发明专利ZL201510742880.4

• 具有降解无机磷和抑菌作用的解淀粉芽孢杆菌及其应用，发明专利ZL201610876823.X

• 具有降解无机磷和抑菌作用的解淀粉芽孢杆菌及其菌剂，发明专利ZL201610876803.2

• 具有降解有机磷和抑菌作用的枯草芽孢杆菌及其菌剂，发明专利ZL201610879210.1

• 具有降解有机磷和抑菌作用的解淀粉芽孢杆菌及其应用，发明专利ZL201610879209.9

• 解淀粉芽孢杆菌HMB28353及其应用，发明专利ZL201710157406.4

• 解淀粉芽孢杆菌HMB28388及其应用，发明专利ZL201710157408.3

• 枯草芽孢杆菌HMB28948及其应用，发明专利ZL201710158062.9

• 枯草芽孢杆菌HMB26553及其应用，发明专利ZL201710157385.6

• NCD-2菌株自组成型启动子及其制备方法和应用，发明专利ZL201910739904.9

• 一种贝莱斯芽孢杆菌HMB28023及其应用，发明专利ZL202010043027.4

• 枯草芽孢杆菌HMB19198菌株的特异性引物、Taqman探针及应用，发明专利ZL202110636409.2

• 防治马铃薯黑痣病的解淀粉芽孢杆菌菌株及菌剂和应用，发明专利ZL201911049405.3

• 马铃薯黑胫病菌的特异性引物、探针及其应用，发明专利ZL202110472615.4

• 一种芽孢杆菌组合物和微生物菌剂及应用，发明专利ZL202210669672.6

主要论文与著作

1. Su, Z., Liu, X., Dong, L., Guo, Q., Li, S., Ma, P., 2024. Complete genome sequence of Bacillus velezensis B31, a potential biocontrol agent with ability of tolerance to fusaric acid and antagonism against Fusarium oxysporum. MICROBIOL RESOUR ANN 13, 1.

2. Su, Z., Liu, G., Li, C., Liu, X., Guo, Q., Wang, P., Dong, L., Lu, X., Zhao, W., Zhang, X., Qu, Y., Zhang, J., Mo, S., Li, S., Ma, P., 2024. Establishment and application of quantitative detection of Bacillus velezensis HMB26553, a biocontrol agent against cotton damping-off caused by Rhizoctonia. BIOTECHNOL J 19, 1.

3. Cui, N., Liang, H., Zhao, W., Zhao, M., Wang, Y., Guo, Q., Rong, Z., Li, S., Ma, P., 2024. Effects of microplastics on potato verticillium wilt and microbial community of rhizosphere soil. APPL SOIL ECOL 203 p.105651-.

4. Zhao, W., Ban, Y., Su, Z., Li, S., Liu, X., Guo, Q., Ma, P., 2023. Colonization Ability of Bacillus subtilis NCD-2 in Different Crops and Its Effect on Rhizosphere Microorganisms. MICROORGANISMS 11.

5. Su, Z., Liu, G., Liu, X., Li, S., Lu, X., Wang, P., Zhao, W., Zhang, X., Dong, L., Qu, Y., Zhang, J., Mo, S., Guo, Q., Ma, P., 2023. Functional Analyses of the Bacillus velezensis HMB26553 Genome Provide Evidence That Its Genes Are Potentially Related to the Promotion of Plant Growth and Prevention of Cotton Rhizoctonia Damping-Off. CELLS-BASEL 12, 1301.

6. Zhao, W., Li, S., Dong, L., Wang, P., Lu, X., Zhang, X., Su, Z., Guo, Q., Ma, P., 2023. Effects of different crop rotations on the incidence of cotton Verticillium wilt and structure and function of the rhizospheric microbial community. PLANT SOIL 485, 457-474.

7. Zhao, W., Wang, P., Dong, L., Li, S., Lu, X., Zhang, X., Su, Z., Guo, Q., Ma, P., 2023. Effect of incorporation of broccoli residues into soil on occurrence of verticillium wilt of spring-sowing-cotton and on rhizosphere microbial communities structure and function. FRONT BIOENG BIOTECH 11, 1115656.Dong, L., Wang, P., Zhao, W., Su, Z., Zhang, X., Lu, X., Li, S., Ma, P., Guo, Q., 2022. Surfactin and fengycin contribute differentially to the biological activity of Bacillus subtilis NCD-2 against cotton verticillium wilt. BIOL CONTROL 174 p.104999-.

8. Zhao, W., Guo, Q., Li, S., Lu, X., Dong, L., Wang, P., Zhang, X., Su, Z., Ma, P., 2022. Application of Bacillus subtilis NCD-2 can suppress cotton verticillium wilt and its effect on abundant and rare microbial communities in rhizosphere. BIOL CONTROL 165 p.104812-.

9. Su, Z., Liu, X., Guo, Q., Xuan, L., Lu, X., Dong, L., Zhang, X., Wang, P., Zhao, W., Qu, Y., Li, S., Ma, P., 2022. Insights into complex infection by two Pectobacterium species causing potato blackleg and soft rot. MICROBIOL RES 261, 127072.

10. Zhao, W., Guo, Q., Li, S.H.O.O., Wang, P., Dong, L., Su, Z., Zhang, X., Lu, X., Ma, P., 2021. Effects of Bacillus subtilis NCD-2 and broccoli residues return on potato Verticillium wilt and soil fungal community structure. BIOL CONTROL 159 p.104628-.

11. Lu, X., Shang, J., Niu, L., Sun, X., Su, Z., Dong, L., Guo, Q.H.O.O., Li, S., Ma, P., 2021. First Report of Verticillium Wilt of Watermelon Caused by Verticillium dahliae in China. PLANT DIS 105.

12. Su, Z., Chen, X., Liu, X., Guo, Q., Li, S., Lu, X., Zhang, X., Wang, P., Dong, L., Zhao, W., Ma, P., 2020. Genome mining and UHPLC–QTOF–MS/MS to identify the potential antimicrobial compounds and determine the specificity of biosynthetic gene clusters in Bacillus subtilis NCD-2. BMC GENOMICS 21, 1-16.

13. Dong, L., Guo, Q., Wang, P., Zhang, X., Su, Z., Zhao, W., Lu, X., Li, S., Ma, P., 2020. Qualitative and Quantitative Analyses of the Colonization Characteristics of Bacillus subtilis Strain NCD-2 on Cotton Root. CURR MICROBIOL 77, 1600-1609.

14. Guo, Q., Dong, L., Wang, P., Su, Z., Liu, X., Zhao, W., Zhang, X., Li, S., Lu, X., Ma, P., 2020. Using a phenotype microarray and transcriptome analysis to elucidate multi-drug resistance regulated by the PhoR/PhoP two-component system in Bacillus subtilis strain NCD-2. MICROBIOL RES 239 p.126557-.

15. GUO, Q., DONG, L., WANG, P., LI, S., ZHAO, W., LU, X., ZHANG, X., Ma, P., 2018. The PhoR/PhoP two-component system regulates fengycin production in Bacillus subtilis NCD-2 under low-phosphate conditions. J INTEGR AGR 17, 149-157.

16. Wang, P., Guo, Q., Li, S., Lu, X., Zhang, X., Ma, P., 2016. Functional analysis of quorum sensing regulator Com A on the production of antifungal active compounds and biofilm formation in Bacillus subtilis NCD-2. Journal of Plant Protection.

17. Zhao, W., Qiu, L., Guo, Q., Xiuyun, L.U., Shezeng, L.I., Wang, P., Zhang, X., Ping, M.A., 2016. Enzymatic degradation characteristics of nicosulfuron by Alcaligenes faecalis ZWS11. Chinese Journal of Pesticide Science.

18. Wang, P., Guo, Q., Ma, Y., Li, S., Lu, X., Zhang, X., Ma, P., 2015. DegQ regulates the production of fengycins and biofilm formation of the biocontrol agent Bacillus subtilis NCD-2. MICROBIOL RES 178, 42-50.

19. Guo, Q., Li, S., Lu, X., Gao, H., Wang, X., Ma, Y., Zhang, X., Wang, P., Ma, P., 2015. Identification of a New Genotype of Fusarium oxysporum f. sp. vasinfectum on Cotton in China. PLANT DIS 99, 1569-1577.

20. Guo, Q., Dong, W., Li, S., Lu, X., Wang, P., Zhang, X., Wang, Y., Ma, P., 2014. Fengycin produced by Bacillus subtilis NCD-2 plays a major role in biocontrol of cotton seedling damping-off disease. MICROBIOL RES 169, 533-540.

21. Guo, Q., Li, S., Lu, X., Zhang, X., Wang, P., Ma, P., 2014. Complete Genome Sequence of Bacillus subtilis BAB-1, a Biocontrol Agent for Suppression of Tomato Gray Mold. Genome announcements 2, p. e00714-p. e00744.

22. Li, S., Jin, X., Chen, J., Lu, S., 2013. Inhibitory activities of venom alkaloids of Red Imported Fire Ant against Clavibacter michiganensis subsp. michiganensis in vitro and the application of piperidine alkaloids to manage symptom development of bacterial canker on tomato in the greenhouse. INT J PEST MANAGE 59, 150-156.

23. Zhang, X., Li, B., Wang, Y., Guo, Q., Lu, X., Li, S., Ma, P., 2013. Lipopeptides, a novel protein, and volatile compounds contribute to the antifungal activity of the biocontrol agent Bacillus atrophaeus CAB-1. APPL MICROBIOL BIOT 97, 9525-9534.

24. Guo, Q., Li, S., Lu, X., Li, B., Stummer, B., Dong, W., Ma, P., 2012. phoR sequences as a phylogenetic marker to differentiate the species in the Bacillus subtilis group. CAN J MICROBIOL 58, 1295-1305.

25. Li, S., Jin, X., Chen, J., 2012. Effects of piperidine and piperideine alkaloids from the venom of red imported fire ants, Solenopsis invicta Buren, on Pythium ultimum Trow growth in vitro and the application of piperideine alkaloids to control cucumber damping-off in the greenhouse. PEST MANAG SCI 68, 1546-1552.

26. Guo, Q., Li, S., Lu, X., Li, B., Ma, P., 2010. PhoR/PhoP two component regulatory system affects biocontrol capability of Bacillus subtilis NCD-2. GENET MOL BIOL 33, 333-340.

27. SUN, H.G., JIANG, J.Z., LI, S.Z., LU, X.Y., MA, P., 2008. Generation of Antibiosis-free Mutants of Bacillus subtilis NCD-2 with Transposon Tn917 and the Role of Antibiosis of NCD-2 in Controlling Cotton Sore Shin. 棉花学报 20, 62-65.

• 《植物病害生物防治学》（普通高等教育“十一五”规划教材） 2010年 科学出版社 参编.

• 《生物农药使用技术百问百答》 2009年 中国农业出版社 参编.

• 《河北省植物病理学研究》第1卷 2003年 中国农业出版社 编者 参编.

• 《北方农作物病虫害实用防治技术》 2002年 中国农业科技出版社 副主编.